Gastric ultrasound in patients receiving semaglutide: a prospective, multicentre, matched control study
Main finding · Full stomachResult — go to the resultOdds ratio 4.29 95% CI 1.63–11.29Authors' conclusion
Our findings highlight a persistently elevated pulmonary aspiration risk, even after withholding one administration of semaglutide and accounting for age, diabetes mellitus status and obesity.
Study context
- Population
- Patients having elective surgery, fasted, with pre-operative gastric ultrasound
- Participants
- 44 vs 44
- Comparison
- Semaglutide vs matched controls
- Semaglutiden = 44
- Controlsn = 44reference
- Outcome
- Full stomach on gastric ultrasound (solid content in any position or right lateral decubitus gastric volume >1.5 ml.kg-1)
Methodological detailsmulticentre, 1:1 matched (age, BMI, DM status)
- Multicentre
- 1:1 matched (age, BMI, DM status)
Main finding
Full stomach
Odds ratio
4.29
95% CI 1.63–11.29
P = 0.003
Events by group
Semaglutide vs Controls
OR 4.29 (95% CI 1.63–11.29); P = 0.003
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Semaglutide | Controls | OR (95% CI) | P value | |
|---|---|---|---|---|---|
| Solid gastric contents | 42% | 7% | 9.85 (2.57–37.76) | P < 0.001 | |
| 0.050.21520Odds ratio (log scale) |
Calculated gastric volume
- Did not differ significantly
Original publication
Gastric ultrasound in patients receiving semaglutide: a prospective, multicentre, matched control study. Anaesthesia. Published 3 February 2026. doi:10.
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