Perioperative medicine & outcomes
Perioperative glucagon-like peptide-1 receptor agonist use and retained gastric contents: A retrospective analysis of patients undergoing elective upper endoscopy
Authors' conclusion
A higher incidence of RGCs was found in appropriately fasted patients on a GLP-1R agonist who presented for UE. After controlling for the differences between the two study groups, RGC's were correlated to GLP-1R agonist use.
Study context
- Population
- Appropriately fasted patients presenting for elective upper gastrointestinal endoscopy (UE), July 2022 to December 2023age-matched
- Participants
- 940 participants
- Exposure
- GLP-1R agonist use vs no GLP-1R agonist use
- GLP-1Rn = 470
- Controlsn = 470reference
- Outcome
- Incidence of retained gastric contents (RGCs)
Methodological detailsretrospective chart review, age-matched controls, propensity-weighted analysis
- Retrospective chart review
- Age-matched controls
- Propensity-weighted analysis
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Secondary outcomes
| Outcome | OR (95 % CI) | |
|---|---|---|
| RGCs, propensity-weighted analysisPropensity-weighted | 1.92 (1.04–3.53) | |
| 0.20.5125Odds ratio (log scale) |
Original publication
Perioperative glucagon-like peptide-1 receptor agonist use and retained gastric contents: A retrospective analysis of patients undergoing elective upper endoscopy. J Clin Anesth. Published 13 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →