Neuroanesthesia & neurocritical care
General anesthesia or conscious sedation for thrombectomy in stroke patients: an updated systematic review and meta-analysis
Authors' conclusion
In this updated systematic review and meta-analysis, the choice of anesthetic strategy for endovascular treatment of stroke patients did not significantly impact functional outcome as measured with the mRS at three months.
Study context
- Population
- Patients undergoing endovascular treatment (thrombectomy) for stroke
- Participants
- 1,342 patients · 9 RCTs
- Comparison
- GA vs conscious sedation for endovascular treatment of stroke
- Outcome
- Functional outcome (modified Rankin scale, mRS)
- Follow-up
- 3 months
Methodological detailstrial sequential analysis, Risk of Bias 2 tool
- Trial sequential analysis
- Risk of Bias 2 tool
Pooled result
As reported in the abstract
mRS
- No significant difference between GA and conscious sedation in modified Rankin scale (mRS)
- Trial sequential analysis: additional trials unlikely to show marked differences in mean mRS at 3 months
Further pooled results
Functional independence (mRS 0-2), procedure duration, onset to reperfusion, mortality, hospital LOS, ICU LOS
- No significant differences between GA and conscious sedation
Successful reperfusion
- May be more frequent with GA
Groin to reperfusion time
- Slightly longer with GA
Original publication
General anesthesia or conscious sedation for thrombectomy in stroke patients: an updated systematic review and meta-analysis. Can J Anaesth. Published 2 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →