Pain medicine

Genetic risk factors for chronic postsurgical pain in children: A narrative review

Eur J AnaesthesiolPublished Systematic review

Authors' conclusion

Evidence has shown that the contribution of genetic risk factors to chronic postsurgical pain development appears to be minor, with its clinical relevance yet to be described.

Study context

Population
Children with chronic postsurgical pain and known or assessed genetic mutations
Outcome
Genetic risk factors for chronic postsurgical pain in children
Methodological detailsSTREGA and Q-Genie quality assessment
  • STREGA and Q-Genie quality assessment

Pooled result

As reported in the abstract

  • Paucity of information on link between genetic mutations and chronic postsurgical pain; some information on acute postoperative pain
  • Contribution of genetic risk factors to chronic postsurgical pain appears minor; clinical relevance yet to be described

Original publication

Genetic risk factors for chronic postsurgical pain in children: A narrative review. Eur J Anaesthesiol. Published 18 May 2023. doi:10.1097/eja.0000000000001847

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