Genomic dynamics of antimicrobial resistance transmission between bacteria from intensive care unit surfaces and from critically ill patients
Authors' conclusion
The findings of this research show that antimicrobial resistance genes are transferred between bacteria on surfaces and bacteria in critically ill patients, and that this transfer occurs in both directions.
Study context
- Population
- Intensive Care Unit (ICU) surfaces and critically ill patients with infections
- Participants
- 130 positive isolates
- Exposure
- Environmental vs Patient
- Environmentaln = 96
- Patientn = 34
- Outcome
- Genomic dynamics of transmission of AMR genes between bacteria from ICU surfaces and from critically ill patients
Methodological detailsanalytical, whole-genome sequencing (nanopore long-read)
- Analytical
- Whole-genome sequencing (nanopore long-read)
Main finding
As reported in the abstract
- Multidrug-resistant (MDR) species identified
- 40 (30.76%)
- Horizontal transfer of resistance genes via plasmid conjugation in suction units, oxygen valves and tracheal secretion
- 3 cases
Observational data: associations, not effects.
Original publication
Genomic dynamics of antimicrobial resistance transmission between bacteria from intensive care unit surfaces and from critically ill patients. Crit Care. Published 1 July 2026. doi:10.
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