Perioperative medicine & outcomes

Guidelines: Diagnosis and management of perioperative immediate hypersensitivity reactions 2025

Anaesth Crit Care Pain MedPublished Clinical practice guideline

Methodological detailsGRADE methodology, GRADE grid voting, PICO questions, PRISMA literature search, 23 French experts from the SFAR and the SFA, Literature search covering the last 24 years, 3 rounds of voting
  • GRADE methodology
  • GRADE grid voting
  • PICO questions
  • PRISMA literature search
  • 23 French experts from the SFAR and the SFA
  • Literature search covering the last 24 years
  • 3 rounds of voting

Recommendations

As issued by the authors

  1. 70 recommendations concerning 31 questions; strong agreement on all 70 after 3 voting rounds

  2. GRADE 1

    6 recommendations with a high level of evidence

  3. GRADE 2

    16 recommendations with a low level of evidence

  4. Expert opinion

    48 recommendations are expert opinions

  5. For 1 question, no recommendation could be made

Original publication

Guidelines: Diagnosis and management of perioperative immediate hypersensitivity reactions 2025. Anaesth Crit Care Pain Med. Published 23 June 2026. doi:10.1016/j.accpm.2026.101867

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