Pediatric anesthesia & critical care
Guidelines for the management of emergencies and critical illness in pediatric and adult patients with sickle cell disease
Methodological detailsGrade of Recommendation Assessment, Development, and Evaluation (GRADE) methodology, expert consensus
- GRADE methodology
- Expert consensus
Recommendations
As issued by the authors
45 recommendations: 14 specific to adults, 13 specific to pediatrics, 18 applicable to both, plus 3 therapeutic algorithms
- GRADE 2+ or 2-
16 recommendations based on low level of evidence
- expert opinion
26 recommendations based on evidence not classifiable under GRADE
No reliable recommendations possible for 3 aspects of sickle cell disease management
Original publication
Guidelines for the management of emergencies and critical illness in pediatric and adult patients with sickle cell disease. Ann Intensive Care. Published 29 May 2025. doi:10.
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