Pediatric anesthesia & critical care

Health Care Burden Associated With Adolescent Prolonged Opioid Use After Surgery

Anesth AnalgPublished Retrospective cohort study

Main finding · Total health care costsResult — go to the resultAdjusted mean difference 4604 $ 95% CI $4027-$5181

Authors' conclusion

In adolescents, POUS was associated with increased total health care costs and utilization in the 730 days after their surgical encounter.

Study context

Population
Opioid-naive US patients 12 to 21 years of age receiving outpatient prescription opioids after surgery (Optum Clinformatics Data Mart, 2003–2019)
Participants
126,338 patients · 132,107 procedures
Exposure
POUS vs non-POUS
  • POUSn = 4,867
Outcome
Total health care costs and visits
Follow-up
730 days after surgery
Methodological detailsinsurance claims database, multivariable regression
  • Insurance claims database
  • Multivariable regression

Main finding

Total health care costs

Adjusted mean difference

4604 $

95% CI $4027-$5181

P < 0.001

POUS vs non-POUS
adjusted mean difference 4604 $ (95% CI $4027-$5181); P < 0.001

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeEstimateP value
Health care utilization · 730 days after surgeryadjusted mean difference, inpatient LOS 0.26 (95% CI 0.22–0.30)P < 0.001
Health care utilization · 730 days after surgeryadjusted mean difference, inpatient visits 0.07 (95% CI 0.07–0.08)P < 0.001
Health care utilization · 730 days after surgeryadjusted mean difference, emergency visits 0.96 (95% CI 0.89–1.03)P < 0.001
Health care utilization · 730 days after surgeryadjusted mean difference, outpatient/other visits 5.78 (95% CI 5.37–6.19)P < 0.001
POUS incidence
3.9% · 4867

Original publication

Health Care Burden Associated With Adolescent Prolonged Opioid Use After Surgery. Anesth Analg. Published 20 June 2022. doi:10.1213/ane.0000000000006111

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