Cardiac arrest & resuscitation
Health-Related Quality of Life and Long-Term Survival After Cardiac Arrest
An erratum to this article was published (JAMA Netw Open, 2 Feb 2026 ↗)
Authors' conclusion
In this cohort study of patients who survived beyond 90 days after IHCA or OHCA, poorer HRQOL reported with EQ-5D-5L scores 3 to 6 months after cardiac arrest was associated with reduced long-term survival in both groups, with greater uncertainty for OHCA estimates.
Study context
- Population
- Adults surviving ≥90 days after in-hospital cardiac arrest (IHCA) or out-of-hospital cardiac arrest (OHCA) in Sweden, 2014–2019, who completed EQ-5D-5L follow-up questionnaires2,000 IHCA, 1108 OHCA
- Exposure
- EQ-5D-5L level sum score (LSS) 6 to 10 and LSS 11 to 25 vs LSS 5, 3 to 6 months after cardiac arrest
- Outcome
- Long-term survival
- Follow-up
- Up to a maximum of 7 years
Methodological detailsnationwide registry linkage (5 national registers)
- Nationwide registry linkage (5 national registers)
Main finding
As reported in the abstract
Hazard of death by LSS category
Each group vs LSS 5Adjusted hazard ratio (95% CI)
LSS 11 to 25IHCA
2.50(1.82–3.43)
LSS 6 to 10IHCA
1.21(0.88–1.65)
LSS 11 to 25OHCA
1.41(0.83–2.42)
LSS 6 to 10OHCA
0.88(0.56–1.39)
Observational data: associations, not effects.
Further findings
LSS and EQ VAS as continuous variables (spline modeling)
- Significant increases in hazards of death with poorer health-related quality of life (HRQOL) in both IHCA and OHCA; greater uncertainty in OHCA
Original publication
Health-Related Quality of Life and Long-Term Survival After Cardiac Arrest. JAMA Netw Open. Published 2 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →