ICU sedation, delirium & recovery
Health related quality of life, physical function, and cognitive performance in mechanically ventilated COVID-19 patients: A long term follow-up study
Authors' conclusion
After 18 months from ICU discharge, survivors of severe COVID-19 respiratory failure experience a moderate reduction in HR-QoL, and a severe reduction in physical functioning. Fatigue prevalence is higher in younger patients and in females. Finally, cognitive impairment was present at a low frequency.
Study context
- Population
- COVID-19 patients who needed invasive mechanical ventilation for COVID-19 related respiratory failure in the Intensive Care Unit (ICU) of Humanitas Research Hospital (Milan, Italy)
- Participants
- 105 patients
- Outcome
- HR-QoL, physical functioning, fatigue and cognitive outcomes
- Follow-up
- 18 months from hospital discharge
Methodological detailscase-series, single-centre
- Case-series
- Single-centre
Main finding
As reported in the abstract
HR-QoL, physical function, fatigue and cognitive performance in invasive mechanical ventilation (IMV) COVID-19 survivors
- EQ-VAS (out of 100)
- 80 [70-90]
- 6MWT walked distance (meters)
- 406 [331-465]
- FACIT-F score (out of 52)
- 43 [36-49]
- MoCA-BLIND score (out of 22)
- 19
- Median Trail Making Test-B (TMT-B) time (seconds)
- 90 [62-120]
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Health related quality of life, physical function, and cognitive performance in mechanically ventilated COVID-19 patients: A long term follow-up study. J Crit Care. Published 13 March 2024. doi:10.
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