ICU sedation, delirium & recovery

Hematologic Malignancies in Critical Care: A National Observational Comparison Between ICU and Non‐ICU Patients

Acta Anaesthesiol ScandPublished Retrospective cohort study

Authors' conclusion

While most HM patients survive ICU admission, long-term survival is decreased compared with non-ICU patients.

Study context

Population
Adults diagnosed with hematologic malignant (HM) and admitted to hospital in Norway, May 6, 2014–December 31, 2019
Participants
26,281 adults
Exposure
ICU vs non-ICU hospitalised patients with HM
  • ICUn = 2,094
Outcome
Long-term survival from first diagnosis until death or December 31, 2020
Methodological detailsnational registry-based
  • National registry-based

Main finding

As reported in the abstract

Mortality vs patients who never required ICU
ICU vs Non-ICUHazard ratio (95% CI)
During ICU care
148(133–165)
After ICU discharge
4.47(4.42–5.07)

Observational data: associations, not effects.

Further findings

Acute leukemia as risk factor for mortality

HR (95% CI)
Acute leukemia4.27 (3.99–4.56)

Survival in ICU cohort

ICU survival
81%
One-year post-ICU survival
45%

Predictors of ICU mortality

Acute leukemia and elevated SAPS II independently predicted ICU mortality; allogeneic transplant status did not

Original publication

Hematologic Malignancies in Critical Care: A National Observational Comparison Between ICU and Non‐ICU Patients. Acta Anaesthesiol Scand. Published 9 April 2026. doi:10.1111/aas.70234

Composed by AI from the published abstract and checked against it. How Briefs are made →

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