ICU sedation, delirium & recovery
Hematologic Malignancies in Critical Care: A National Observational Comparison Between ICU and Non‐ICU Patients
Authors' conclusion
While most HM patients survive ICU admission, long-term survival is decreased compared with non-ICU patients.
Study context
- Population
- Adults diagnosed with hematologic malignant (HM) and admitted to hospital in Norway, May 6, 2014–December 31, 2019
- Participants
- 26,281 adults
- Exposure
- ICU vs non-ICU hospitalised patients with HM
- ICUn = 2,094
- Outcome
- Long-term survival from first diagnosis until death or December 31, 2020
Methodological detailsnational registry-based
- National registry-based
Main finding
As reported in the abstract
Mortality vs patients who never required ICU
ICU vs Non-ICUHazard ratio (95% CI)
During ICU care
148(133–165)
After ICU discharge
4.47(4.42–5.07)
Observational data: associations, not effects.
Further findings
Acute leukemia as risk factor for mortality
| HR (95% CI) | ||
|---|---|---|
| Acute leukemia | 4.27 (3.99–4.56) | |
| 0.20.5125Hazard ratio (log scale) |
Survival in ICU cohort
- ICU survival
- 81%
- One-year post-ICU survival
- 45%
Predictors of ICU mortality
- Acute leukemia and elevated SAPS II independently predicted ICU mortality; allogeneic transplant status did not
Original publication
Hematologic Malignancies in Critical Care: A National Observational Comparison Between ICU and Non‐ICU Patients. Acta Anaesthesiol Scand. Published 9 April 2026. doi:10. 1111/ aas. 70234
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