Hemodynamic changes in patients with SARS-CoV-2 infection presenting for cesarean delivery under spinal anesthesia: a retrospective case-control study
Authors' conclusion
Patients with SARS-CoV-2 infection during pregnancy exhibit less spinal hypotension than non-infected patients.
Study context
- Population
- Pregnant patients receiving spinal anesthesia for cesarean delivery
- Participants
- 22 / 73 / 1,517
- Comparison
- SARS-CoV-2 positive at delivery or recovered before delivery vs SARS-CoV-2 negative controls
- SARS-CoV-2 positiven = 22
- SARS-CoV-2 recoveredn = 73
- Controlsn = 1,517reference
- Outcome
- Post-spinal MAP (hemodynamic response to spinal anesthesia)
Methodological detailstwo tertiary care hospitals, historical controls, stratified by normotensive vs hypertensive status
- Two tertiary care hospitals
- Historical controls
- Stratified by normotensive vs hypertensive status
Main finding
As reported in the abstract
Post-spinal MAP
Difference
5.6 mmHg
SARS-CoV-2 positive
Difference
2.2 mmHg
SARS-CoV-2 recovered
Observational data: associations, not effects.
Further findings
Lowest post-spinal MAP vs days from COVID-19 symptom onset to delivery (hypertensive patients)
- Correlation (negative)
- −0.55
- 95% CI −0.81 to −0.09
Original publication
Hemodynamic changes in patients with SARS-CoV-2 infection presenting for cesarean delivery under spinal anesthesia: a retrospective case-control study. Int J Obstet Anesth. Published 28 December 2022. doi:10.
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