Hemodynamics, fluids & transfusion
Hemoglobin in cardiogenic shock: the lower, the poorer survival
Authors' conclusion
Anemia is a common condition frequently intertwined with CS worsening both short- and long-term mortality.
Study context
- Population
- Cardiogenic shock patients, FRENSHOCK registry, 49 centres754 analysed
- Participants
- 772 patients
- Exposure
- Admission hemoglobin (Hb) quartiles
- Outcome
- All-cause mortality by admission Hb level
- Follow-up
- 1 month and 1 year
Methodological detailsmulticentre registry
- Multicentre registry
Main finding
As reported in the abstract
All-cause mortality
Higher mortality (times)
1.64
CI 1.09–2.47P = 0.02
1 month
Higher mortality (times)
2.53
CI 1.84–3.49P < 0.01
1 year
- Significant increase in mortality across Hb quartiles at 1 month
- P for trend = 0.035
- Significant increase in mortality across Hb quartiles at 1 year
- P for trend < 0.01
Observational data: associations, not effects.
Further findings
Anaemia at admission
- Patients presenting with anemia
- 361 (47.9%)
RRT and norepinephrine use
- More frequent in Q1
Adjusted mortality (multivariate Cox regression) and subgroups
- Negative effect of low Hb confirmed after adjustment; stronger in men, non-ischemic cardiogenic shock (CS), patients without CKD and aged < 67 years
Original publication
Hemoglobin in cardiogenic shock: the lower, the poorer survival. J Intensive Care. Published 23 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →