Cardiothoracic & vascular anesthesia

Hemolysis during open heart surgery in patients with hereditary spherocytosis — systematic review of the literature and case study

Perioper Med (Lond)Published Systematic review of the literature and case study

Authors' conclusion

The literature data show that hemolysis is not common in patients with HS undergoing various cardiac surgery techniques.

Study context

Population
Patients with hereditary spherocytosis (HS) undergoing cardiac surgery
Participants
23 patients · 21 studies
Outcome
Hemolysis after cardiac surgery
Methodological detailsEmbase, MEDLINE, Web of Science, Google Scholar searched; 787 search results
  • Embase, MEDLINE, Web of Science, Google Scholar searched; 787 search results

Pooled result

As reported in the abstract

Hemolysis
Hemolysis diagnosed (1 CABG, 2 aortic valve bioprosthesis, 1 ventricular septal defect closure, 1 mitral valve plasty)
5

Further pooled results

Case study: 38-year-old patient, aortic valve repair · perioperative period

No significant clinical hemolysis

Perioperative death · perioperative period

None of the patients died
0

Original publication

Hemolysis during open heart surgery in patients with hereditary spherocytosis — systematic review of the literature and case study. Perioper Med (Lond). Published 10 June 2024. doi:10.1186/s13741-024-00411-w

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