Cardiac arrest & resuscitation
Heparin Loading Dose in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation
Authors' conclusion
In conclusion, in the authors' study of patients undergoing ECPR, administering a loading dose of heparin was associated with an increased risk of early fatal hemorrhage.
Study context
- Population
- Patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR) after cardiac arrest in the ED of the Aerospace Center Hospital, January 2018 to May 2022
- Participants
- 28 patients
- Exposure
- Heparin loading dose before catheterization vs no loading dose
- Loading-dosen = 12
- Nonloading-dosen = 16reference
- Outcome
- Hemorrhagic complications
Methodological detailsmonocentric
- Monocentric
Main finding
As reported in the abstract
P > 0.05
Observational data: associations, not effects.
Further findings
Embolic complications · not statistically significant
P > 0.05
Survival · not statistically significant
P > 0.05
Safety
Life-threatening massive hemorrhage · statistically significant
P = 0.03
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Heparin Loading Dose in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation. J Cardiothorac Vasc Anesth. Published 22 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →