Respiratory failure & ventilation
High‐Flow Tracheal Oxygen for Weaning Mechanically Ventilated Tracheostomized Critically Ill Patients: A Retrospective Study
Authors' conclusion
The timing of HFTO initiation (early vs. rescue) in tracheostomized patients may not have an impact on the rate of liberation from MV at 60 days.
Study context
- Population
- Mechanically ventilated tracheostomized ICU patients receiving high-flow tracheal oxygen (HFTO) for mechanical ventilation (MV) weaning, 2018–2024
- Participants
- 77 participants
- Exposure
- Early vs rescue high-flow tracheal oxygen for MV weaning
- Outcome
- Successful MV liberation from the first successful separation attempt (tolerating ≥ 1 h off MV)
- Follow-up
- 60 days
Main finding
As reported in the abstract
P = 0.679
Observational data: associations, not effects.
Secondary outcomes
VFDs at 60 days · no difference
P = 0.702
Factors associated with successful MV weaning
| OR for successful MV weaning (lower odds) (95% CI) | ||
|---|---|---|
| Male genderAssociated with lower odds of successful MV weaning | 0.24 (0.06–0.88) | |
| HypertensionAssociated with lower odds of successful MV weaning | 0.24 (0.07–0.82) | |
| 0.050.21520OR for successful MV weaning (lower odds) (log scale) |
Successful MV weaning, overall cohort · 60 days
- Successfully weaned from MV at 60 days, all patients
- 57 (74.0%)
Original publication
High‐Flow Tracheal Oxygen for Weaning Mechanically Ventilated Tracheostomized Critically Ill Patients: A Retrospective Study. Acta Anaesthesiol Scand. Published 11 August 2025. doi:10. 1111/ aas. 70104
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