Anaesthetic drugs & techniques
High-Frequency Low-Tidal Volume Ventilation and Procedural Efficiency in Atrial Fibrillation Catheter Ablation: A Single-Center Retrospective Study
Main findingResult — go to the resultNonstandardized β (ablation time, multivariable regression) −5.48 minutes 95% CI −7.05 to −3.91Authors' conclusion
In a consecutive cohort including paroxysmal and persistent AF, HFLTV was associated with shorter procedure and ablation times and lower measured airway pressures without compromising gas exchange.
Study context
- Population
- Consecutive adults undergoing first-time atrial fibrillation (AF) radiofrequency ablation under GA (propofol-remifentanil TIVA), single tertiary university hospital, June 2023–May 2024
- Participants
- 160 consecutive eligible adults
- Exposure
- High-frequency low-tidal volume ventilation vs standard ventilation
- High-frequency low-tidal volume (HFLTV)n = 80
- Standard ventilation (SV)n = 80reference
- Outcome
- Total procedure time and radiofrequency ablation time
Methodological detailsobservational, nonrandomized, single-centre
- Observational
- Nonrandomized
- Single-centre
Main finding
As reported in the abstract
Nonstandardized β (ablation time, multivariable regression)
−5.48 minutes
95% CI −7.05 to −3.91
P < 0.001
By group
Observational data: associations, not effects.
Secondary outcomes
Peak airway pressure
P < 0.001
Minimum airway pressure
P < 0.001
AF recurrence · 1 month · exploratory analysis
P = 0.211
AF recurrence · 6 months · exploratory analysis
P = 0.520
AF-related hospitalization · 6 months · exploratory analysis; CIs wide and included no difference
P = 0.384
ETCO₂ and SpO2 nadir
- Comparable between groups
Original publication
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