Neuroanesthesia & neurocritical care
High frequency oscillations may improve somatosensory evoked potential detection of good outcomes in disorders of consciousness secondary to acute neurologic injury
Authors' conclusion
Incorporation of this measure may improve the specificity of the SEP to predict in-hospital GCS outcomes in coma, but requires further validation in specific neurologic injuries and with longitudinal outcomes.
Study context
- Population
- Comatose inpatients (Glasgow Coma Scale (GCS)<=8) undergoing neurologic prognostication, Johns Hopkins Hospital, 2020–2022; analysis in those with bilaterally present N20s34 with bilateral N20s
- Participants
- 58 inpatients
- Comparison
- SEP with HFO evoked to spontaneous ratios (HFO-ESRs) vs bilaterally present N20s alone
- Outcome
- Prediction of final GCS>=9 (last documented in-hospital GCS prior to discharge or death)
Methodological detailspilot, single-centre
- Pilot
- Single-centre
Performance
As reported in the abstract
Specificity for final GCS>=9
| Test or model | Specificity |
|---|---|
| Univariate HFO-ESR | 68% |
| SVM | 85% |
Specificity
Univariate HFO-ESR68%
SVM85%
Original publication
High frequency oscillations may improve somatosensory evoked potential detection of good outcomes in disorders of consciousness secondary to acute neurologic injury. Resuscitation. Published 24 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →