Neuroanaesthesia & neurocritical care

The Glasgow Coma Scale as a predictor of mortality in intensive care: relevance of underlying cause of impaired consciousness

J Crit CarePublished Retrospective register-based cohort study

Authors' conclusion

Low GCS was a strong predictor of death, but its relative weight was highly dependent on the diagnosis.

Study context

Population
Admissions to 20 Intensive Care Unit (ICUs) in Finland, Estonia, and Switzerland, 2015–2017admissions, 20 ICUs
Participants
58,982 admissions
Exposure
Low GCS vs higher GCS, by diagnosis category
  • Neurologicn = 17,275
  • Other diagnosesn = 41,707
Outcome
Association between low GCS (lowest GCS in first 24 h after ICU admission below 9) and risk of death
Methodological detailsmulticentre, hierarchical logistic regression
  • Multicentre
  • Hierarchical logistic regression

Main finding

As reported in the abstract

Risk of death with low GCS
Low GCS vs not, within category
Odds ratio (95% CI)
Neurologic
11.3(8.0–15.9)
Other diagnoses
4.8(3.9–5.8)

Observational data: associations, not effects.

Further findings

Prevalence of low GCS · first 24 h

Original publication

The Glasgow Coma Scale as a predictor of mortality in intensive care: relevance of underlying cause of impaired consciousness. J Crit Care. Published 30 April 2026. doi:10.1016/j.jcrc.2026.155605

Composed by AI from the published abstract and checked against it. How Briefs are made →

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