Cardiac arrest & resuscitation
High‐sensitivity troponin T for detection of culprit lesions in patients with out‐of‐hospital cardiac arrest
Authors' conclusion
HsTnT levels after cardiac arrest are higher in patients with coronary culprit lesions.
Study context
- Population
- Patients admitted to the ICU after out-of-hospital cardiac arrest (OHCA) who received coronary angiography
- Participants
- 238 patients
- Exposure
- Culprit lesion vs no culprit lesion at coronary angiography
- Culprit lesionn = 140
- Outcome
- Peak hsTnT levels (hypothesis: higher in patients with a coronary culprit lesion)
- Follow-up
- Initial 48 h after cardiac arrest
Main finding
As reported in the abstract
hsTnT levels · initial 48 h
- High-sensitivity troponin T (hsTnT) levels higher in patients with culprit lesions
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Diagnostic accuracy of hsTnT cut-off 1690 ng/L for culprit lesion · 6 to 12 h after ROSC | hsTnT sensitivity 64% · specificity 84% |
| Diagnostic accuracy of hsTnT for culprit lesion (subgroup without ST-elevations) · between 6 and 12 h after ROSC | hsTnT specificity above 90% · sensitivity 46% |
Factors affecting hsTnT levels · initial 48 h
- hsTnT higher with longer time to return of spontaneous circulation (ROSC) and an unwitnessed cardiac arrest
Original publication
High‐sensitivity troponin T for detection of culprit lesions in patients with out‐of‐hospital cardiac arrest. Acta Anaesthesiol Scand. Published 31 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →