Perioperative medicine & outcomes
Higher versus Routine Intraoperative Blood Pressure Targets in Noncardiac Surgery: A Systematic Review and Meta-analysis with Trial Sequential Analysis of Randomized Trials
Pooled result · AKIResult — go to the resultRelative risk 0.95 95% CI 0.85–1.06Authors' conclusion
In adults undergoing elective noncardiac surgery, targeting higher intraoperative blood pressure values does not improve major postoperative outcomes compared with routine management.
Study context
- Population
- Adults undergoing elective noncardiac surgery with GA
- Participants
- 15,603 adults · 15 trials
- Comparison
- Higher intraoperative BP targets vs routine BP management
- Outcome
- Acute kidney injury (AKI)
Methodological detailstrial sequential analysis, PRISMA-guided
- Trial sequential analysis
- PRISMA-guided
Pooled result
As reported in the abstract
Relative risk
0.95
95% CI 0.85–1.06
P = 0.36
Higher targets vs Routine targets
RR 0.95 (95% CI 0.85–1.06); P = 0.36
Further pooled results
| Outcome | RR (95% CI) | P value | |
|---|---|---|---|
| Postoperative deliriumI 2 = 26% | 0.73 (0.54–0.98) | P = 0.04 | |
| 0.512Relative risk (log scale) |
- Postoperative delirium: trial sequential analysis: cumulative evidence insufficient to draw firm conclusions
30-day major cardiovascular events, stroke, LOS
- Evidence insufficient to draw firm conclusions
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Higher versus Routine Intraoperative Blood Pressure Targets in Noncardiac Surgery: A Systematic Review and Meta-analysis with Trial Sequential Analysis of Randomized Trials. Anesthesiology. Published 4 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →