Cardiac arrest & resuscitation
In-hospital extracorporeal cardiopulmonary resuscitation for patients with out-of-hospital cardiac arrest: an analysis by time-dependent propensity score matching using a nationwide database in Japan
Authors' conclusion
ECPR was associated with increased 30-day survival in patients with OHCA with initial shockable and even non-shockable rhythms.
Study context
- Population
- Adults (≥ 18 years) with out-of-hospital cardiac arrest (OHCA), JAAM-OHCA registry, Japan, June 2014–December 2019registry
- Participants
- 57,754 adults
- Comparison
- Extracorporeal cardiopulmonary resuscitation (ECPR) vs control, by initial rhythm
- ECPR (shockable)n = 913
- Control (shockable)n = 913reference
- ECPR (non-shockable)n = 370
- Control (non-shockable)n = 370reference
- Primary endpoint
- 30-day survival
- Follow-up
- 30 days
Methodological detailsnationwide multicentre prospective registry, time-dependent propensity-score matched (risk-set matching)
- Nationwide multicentre prospective registry
- Time-dependent propensity-score matched (risk-set matching)
Primary result
As reported in the abstract
ECPR vs ControlOR for 30-day survival (95% CI)
Shockable rhythm
1.76(1.38–2.25)
Non-shockable rhythm
5.37(2.53–11.43)
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| 30-day favorable neurological outcome · 30 daysECPR (shockable) vs Control (shockable) · shockable rhythm · matched cohorts | 1.11 (0.82–1.49) | |
| 30-day favorable neurological outcome · 30 daysECPR (non-shockable) vs Control (non-shockable) · non-shockable rhythm · matched cohorts | 4.25 (1.43–12.63) | |
| 0.050.21520Odds ratio (log scale) |
Original publication
In-hospital extracorporeal cardiopulmonary resuscitation for patients with out-of-hospital cardiac arrest: an analysis by time-dependent propensity score matching using a nationwide database in Japan. Crit Care. Published 15 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →