ICU sedation, delirium & recovery
In-hospital outcomes after acute myocardial infarction with obstructive coronary artery disease in critically ill patients hospitalized for non-cardiac disease
Authors' conclusion
Patients who have an AMI with OCAD during an ICU stay for non-cardiac disease are at risk of a composite outcome of severe ischemia, major bleeding, and death. A history of arterial hypertension and high SOFA scores were independent hazards for poor prognosis.
Study context
- Population
- Adults admitted to intensive care unit (ICU) for non-cardiac disease with acute myocardial infarction (AMI) with obstructive coronary artery disease during ICU stay, 4 French university hospital ICUs, 2012–2018
- Participants
- 96 adults
- Outcome
- In-hospital occurrence of the composite outcome
- Follow-up
- In-hospital
Methodological detailsmulticentre, consecutive patients
- Multicentre
- Consecutive patients
Main finding
As reported in the abstract
Composite outcome
Composite outcome occurred
48
50%
Observational data: associations, not effects.
Further findings
Independent risk factors for composite outcome
| HR (95% CI) | ||
|---|---|---|
| History of arterial hypertension | 2.05 (1.01–4.16) | |
| High SOFA score at time of AMI | 1.07 (1.00–1.15) | |
| 0.20.5125Hazard ratio (log scale) |
Severe ischemic events · in-hospital
- Severe ischemic events
- 17 (18%)
In-hospital death
- Died in hospital
- 26 (27%)
AMI management by composite outcome
- AMI management not significantly different in patients with and without the composite outcome
Safety
Major bleeding · in-hospital
- Major bleeding
- 26 (27%)
Original publication
In-hospital outcomes after acute myocardial infarction with obstructive coronary artery disease in critically ill patients hospitalized for non-cardiac disease. Ann Intensive Care. Published 19 September 2023. doi:10.
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