Hypernatremia in Hospitalised Adult Patients—A Scoping Review
An erratum to this article was published (Acta Anaesthesiol Scand, Jan 2026 ↗)
Authors' conclusion
In this scoping review, hypernatremia was present in 3.5% of the patients in non-ICU studies and in 21.8% in ICU studies.
Study context
- Population
- Hospitalised adults with hypernatremia
- Participants
- 200 studies
- Comparison
- Non-ICU vs intensive care unit (ICU)
- Non-ICUn = 89
- ICUn = 111
- Outcome
- Occurrence of hypernatremia, treatment strategies, treatment-associated serious adverse events and reported outcomes
Methodological detailsPRISMA extension for Scoping Reviews, pre-published protocol
- PRISMA extension for Scoping Reviews
- Pre-published protocol
Main finding
As reported in the abstract
Proportion of patients with hypernatremia
Further findings
Reported treatments of hypernatremia
- Hypotonic fluids (studies)
- 3
- Thiazide diuretics (studies)
- 3
- RRT (studies)
- 4
Patient-important outcomes reported
- Mortality, studies
- 186 (93.0%)
- ICU or hospital LOS, studies
- 109 (54.5%)
- Mechanical ventilation, studies
- 47 (23.5%)
Safety
Treatment-associated serious adverse events
- Rarely reported
Original publication
Hypernatremia in Hospitalised Adult Patients—A Scoping Review. Acta Anaesthesiol Scand. Published 13 October 2025. doi:10. 1111/ aas. 70132
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