Organ support & nutrition

Hypernatremia in Hospitalised Adult Patients—A Scoping Review

Acta Anaesthesiol ScandPublished Scoping review

An erratum to this article was published (Acta Anaesthesiol Scand, Jan 2026 ↗)

Authors' conclusion

In this scoping review, hypernatremia was present in 3.5% of the patients in non-ICU studies and in 21.8% in ICU studies.

Study context

Population
Hospitalised adults with hypernatremia
Participants
200 studies
Comparison
Non-ICU vs intensive care unit (ICU)
  • Non-ICUn = 89
  • ICUn = 111
Outcome
Occurrence of hypernatremia, treatment strategies, treatment-associated serious adverse events and reported outcomes
Methodological detailsPRISMA extension for Scoping Reviews, pre-published protocol
  • PRISMA extension for Scoping Reviews
  • Pre-published protocol

Main finding

As reported in the abstract

Proportion of patients with hypernatremia

Further findings

Reported treatments of hypernatremia

Hypotonic fluids (studies)
3
Thiazide diuretics (studies)
3
RRT (studies)
4

Patient-important outcomes reported

Mortality, studies
186 (93.0%)
ICU or hospital LOS, studies
109 (54.5%)
Mechanical ventilation, studies
47 (23.5%)

Safety

Treatment-associated serious adverse events

Rarely reported

Original publication

Hypernatremia in Hospitalised Adult Patients—A Scoping Review. Acta Anaesthesiol Scand. Published 13 October 2025. doi:10.1111/aas.70132

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