Use of prokinetic agents in hospitalised adult patients: A scoping review
Authors' conclusion
In this scoping review, we found that the studies addressing prokinetic agents in hospitalised adults had considerable variations in indications, drugs and outcomes assessed, and that the certainty of evidence was judged to be low to very low.
Study context
- Population
- Adult hospitalised patients receiving prokinetic agents for any indication
- Participants
- 8,830 participants · 102 studies
- Outcome
- Body of evidence on prokinetic agents
Methodological detailsPRISMA-ScR, modified Grading of Recommendations Assessment, Development and Evaluation (GRADE) certainty assessment
- PRISMA-ScR
- Modified GRADE certainty assessment
Main finding
As reported in the abstract
- Clinical trials
- 86 (84%)
- Trials conducted in ICU (main indication feeding intolerance)
- 52 (60%)
- Studies of metoclopramide
- 49%
- Studies of erythromycin
- 31%
- Outcomes assessed
- 147
- Studies assessing patient-centred outcomes
- 67%
Original publication
Use of prokinetic agents in hospitalised adult patients: A scoping review. Acta Anaesthesiol Scand. Published 8 March 2023. doi:10.
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