ICU sedation, delirium & recovery

Hypocalcemia in critical care settings, from its clinical relevance to its treatment: A narrative review

Anaesth Crit Care Pain MedPublished Narrative review

Authors' conclusion

We concluded that hypocalcemia is associated with several important clinical outcomes.

Study context

Population
Critically ill patients with hypocalcemia (measured through ionized calcium), incl. trauma and sepsis subgroups
Comparison
Calcium supplementation vs no supplementation for hypocalcemia
Methodological detailsLiterature search: PubMed, Web of Science, Cochrane Library, Google Scholar
  • Literature search: PubMed, Web of Science, Cochrane Library, Google Scholar

Main finding

As reported in the abstract

  • Hypocalcemia associated with high mortality and disease severity in critically ill patients (several studies)
  • Evidence on correction conflicting; most studies: calcium supplementation did not improve clinical outcomes, such as mortality
  • In some cases, ionized calcium normalized without supplementation

Further findings

Trauma and sepsis (subgroup)

Subgroups with special characteristics to consider when treating hypocalcemia

Original publication

Hypocalcemia in critical care settings, from its clinical relevance to its treatment: A narrative review. Anaesth Crit Care Pain Med. Published 11 October 2024. doi:10.1016/j.accpm.2024.101438

Composed by AI from the published abstract and checked against it. How Briefs are made →

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