Hemodynamics, fluids & transfusion
Hypotension during intensive care stay and mortality and morbidity: a systematic review and meta-analysis
Pooled result · MortalityResult — go to the resultOdds ratio 1.45 95% CI 1.12–1.88Authors' conclusion
Exposure to hypotension during ICU stay was associated with increased mortality and AKI in the majority of included studies, and associations for both outcomes increased with increasing hypotension severity. The meta-analysis reinforced the descriptive findings regarding mortality but did not yield similar support for AKI.
Study context
- Population
- Intensive care unit (ICU) patients
- Participants
- 176,329 patients · 122 studies
- Comparison
- Hypotension vs no hypotension during ICU stay
- Outcome
- Mortality and morbidity (11 predefined outcomes)
Methodological detailstwo independent reviewers, risk of bias assessment, CENTRAL, Embase and PubMed searched up to October 2022
- Two independent reviewers
- Risk of bias assessment
- CENTRAL, Embase and PubMed searched up to October 2022
Pooled result
Mortality
Odds ratio
1.45
95% CI 1.12–1.88
Hypotension vs No hypotension
OR 1.45 (95% CI 1.12–1.88)
As reported in the abstract
Further pooled results
Acute kidney injury (AKI) (meta-analysis)
- No significant association between hypotension and AKI
Original publication
Hypotension during intensive care stay and mortality and morbidity: a systematic review and meta-analysis. Intensive Care Med. Published 22 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →