Hypotension prediction index for prevention of intraoperative hypotension in patients undergoing general anesthesia: a randomized controlled trial
Authors' conclusion
HPI guidance appears to be effective in preventing intraoperative hypotension during general anesthesia.
Study context
- Population
- Patients undergoing GA with invasive arterial monitoring60 completed
- Participants
- 30 vs 30
- Comparison
- Hypotension Prediction Index (HPI)-guided hemodynamic management vs standard of care
- Interventionn = 30
- Controln = 30reference
- Primary endpoint
- Hypotension severity (TWA MAP < 65 mmHg)
Methodological detailssingle-centre, tertiary referral hospital
- Single-centre
- Tertiary referral hospital
Primary result
As reported in the abstract
TWA MAP < 65 mmHg
Intervention
0.02
median · interval 0.003–0.08
Control
0.37
median · interval 0.20–0.58
P < 0.001
Secondary outcomes
Median MAP during surgery · significantly higher with intervention
P < 0.001
Time-weighted average (TWA) mean arterial pressure (MAP) < 60 mmHg and < 55 mmHg
- Findings similar to primary outcome
Original publication
Hypotension prediction index for prevention of intraoperative hypotension in patients undergoing general anesthesia: a randomized controlled trial. Perioper Med (Lond). Published 15 June 2024. doi:10.
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