Perioperative medicine & outcomes
Identifying Risk of Postoperative Cardiorespiratory Complications in OSA
Authors' conclusion
These findings provide a basis for better identifying high-risk patients with OSA and determining appropriate postoperative care.
Study context
- Population
- Consecutive patients with diagnostic polysomnography for possible OSA and a procedure under GA within 2 years before to at least 5 years after polysomnography
- Participants
- 6,770 patients
- Exposure
- OSA severity measures (polysomnography-derived) and other predictors of postoperative cardiorespiratory complications or death
- Outcome
- Composite of:
- Cardiorespiratory complications
- Death
- Follow-up
- Within 30 days of hospital discharge
Methodological detailsconsecutive patients, linked polysomnography and health databases, multivariable analysis
- Consecutive patients
- Linked polysomnography and health databases
- Multivariable analysis
Main finding
As reported in the abstract
Composite cardiorespiratory complications or death within 30 days of discharge (independent predictors, multivariable analysis) · 30 days of hospital discharge
Odds ratio (95% CI)P value
Age older than 65 years
2.67(2.03–3.52)
P < 0.0001Age 55.1 to 65 years
1.47(1.09–1.98)
P = 0.0111Time between polysomnography and procedure ≥ 5 years
1.32(1.02–1.70)
P = 0.0331BMI ≥ 35 kg/m²
1.43(1.13–1.82)
P = 0.0032Known cardiorespiratory risk factor
1.63(1.29–2.06)
P < 0.0001> 4.7% of sleep time at an oxygen saturation measured by pulse oximetry of < 90% (T90)
1.91(1.51–2.42)
P < 0.0001Cardiothoracic procedures
7.95(5.71–11.08)
P < 0.0001- Primary outcome observed in the cohort
- 5.3% (n = 361)
Observational data: associations, not effects.
Further findings
Noncardiothoracic procedures: risk score (age, BMI, known cardiorespiratory risk factor, T90)
- Risk score AUC (ROC)
- 0.7 (95% CI, 0.64-0.75)
- Age, BMI, known cardiorespiratory risk factor and T90 remained significant predictors
Original publication
Identifying Risk of Postoperative Cardiorespiratory Complications in OSA. Chest. Published 10 August 2024. doi:10.
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