Cardiothoracic & vascular anesthesia
Impact of Electroencephalography-guided Anesthesia in Cardiothoracic Surgery: A Systematic Review and Updated Meta-analysis of Randomized Controlled Trials
Authors' conclusion
The findings demonstrated that EEG-guided anesthesia was associated with a shorter duration of respiratory support. However, this study did not identify any significant comparative advantage over standard practices for the other outcomes analyzed.
Study context
- Population
- Patients undergoing cardiothoracic surgery
- Participants
- 2,666 patients · 8 randomized clinical trials (RCTs)
- Comparison
- EEG-guided vs non-EEG-guided anaesthesia
- EEG-guided anesthesian = 1,304
- Usual caren = 1,362reference
- Outcome
- Pooled outcomes, EEG-guided vs non-EEG-guided anesthesia
Methodological detailsrandom-effects model
- Random-effects model
Pooled result
As reported in the abstract
- Ventilatory support duration: trend toward reduction with EEG-guided anesthesia
- MD −25.08 −25.08 (95% CI −50.12 to −0.04, p = 0.05, I² = 0%)
- Postoperative delirium: no significant difference
- RR 0.93 0.93 (95% CI 0.79-1.09, p = 0.35, I² = 42.6%)
- Hospital LOS: no significant difference
- MD −0.22 −0.22 (95% CI −0.53 to 0.09, p = 0.17, I² = 4.7%)
- ICU LOS: no significant difference
- MD −0.24 −0.24 (95% CI −0.59 to 0.12, p = 0.19, I² = 71.7%)
- Mortality: no significant difference
- RR 0.82 0.82 (95% CI 0.54-1.25, p = 0.36, I² = 42%)
- Intraoperative blood transfusion: no significant difference
- RR 0.96 0.96 (95% CI 0.74-1.25, p = 0.79, I² = 0%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Impact of Electroencephalography-guided Anesthesia in Cardiothoracic Surgery: A Systematic Review and Updated Meta-analysis of Randomized Controlled Trials. J Cardiothorac Vasc Anesth. Published 25 June 2025. doi:10.
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