Impact of ketamine infusions on healthcare utilization and chronic pain: a comparative effectiveness study with insights from real-world data
Main finding · Pain-related visitsResult — go to the resultReduction 45%Authors' conclusion
IV ketamine was more effective than conventional therapy in reducing unexpected pain-related healthcare utilization for over 6 months in patients with chronic pain.
Study context
- Population
- Patients with chronic pain, University of Pittsburgh Medical Center healthcare networkmatched cohort
- Participants
- 118 vs 118
- Comparison
- Intravenous (IV) ketamine infusions vs matched control cohort
- Ketaminen = 118
- Controln = 118reference
- Outcome
- Unexpected pain-related healthcare utilization (ED visits, urgent care visits, hospital admissions)
- Follow-up
- 6 months before and after ketamine infusion
Methodological detailspropensity score-matched, real-world data
- Propensity score-matched
- Real-world data
Main finding
Pain-related visits · 6 months
Reduction
45%
P < 0.001
As reported in the abstract
Original publication
Impact of ketamine infusions on healthcare utilization and chronic pain: a comparative effectiveness study with insights from real-world data. Reg Anesth Pain Med. Published 3 March 2026. doi:10.
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