Perioperative medicine & outcomes
Impact of postoperative cardiovascular complications on 30‐day mortality after major abdominal surgery: an international prospective cohort study
Authors' conclusion
Postoperative cardiovascular complications are relatively common and occur early after major abdominal surgery. However, over 1 in 5 postoperative deaths were attributable to these complications
Study context
- Population
- Consecutive patients undergoing major abdominal surgery in 446 hospitals from 28 countries across Europe, January–May 2022
- Participants
- 24,203 patients · 446 hospitals
- Exposure
- Postoperative cardiovascular complications vs none
- Cardiovascular complicationsn = 611
- Outcome
- Cardiovascular complications (StEP-COMPAC definition)
- Follow-up
- Up to 30 days after surgery
Methodological detailsinternational, multicentre
- International
- Multicentre
Main finding
As reported in the abstract
Incidence of cardiovascular complications
Patients developing cardiovascular complications
611
2.5%
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Cardiovascular complications | No complications | HR (95% CI) | |
|---|---|---|---|---|
| 30-day mortality · up to 30 daysAfter risk adjustment | 19.8% | 1.4% | 4.15 (3.14–5.48) | |
| 0.20.5125Hazard ratio (log scale) |
- 30-day mortality — Overall deaths within 30 days
- 458 (1.9%)
- 30-day mortality — Deaths judged cardiac-related
- 123 (26.9%)
- 30-day mortality — Absolute risk reduction in mortality in absence of all cardiovascular complications
- 0.4 (95%CI 0.3-0.5)
- 30-day mortality — Relative risk reduction in mortality if all cardiovascular complications prevented
- 21.1%
Original publication
Impact of postoperative cardiovascular complications on 30‐day mortality after major abdominal surgery: an international prospective cohort study. Anaesthesia. Published 2 February 2024. doi:10.
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