Perioperative medicine & outcomes
Impact of Preoperative Immunonutrition on the Outcomes of Colon Cancer Surgery: Results from a Randomized Controlled Trial
Authors' conclusion
Preoperative immunonutrition was not associated with infectious complications in patients undergoing colon cancer surgery.
Study context
- Population
- Patients with primary colon cancer undergoing elective surgery
- Participants
- 176 patients
- Comparison
- Preoperative immunonutrition plus normal diet vs normal diet alone
- Immunonutritionn = 88
- Normal dietn = 88reference
- Primary endpoint
- Rate of infectious complications
Methodological detailsEnrolled April 2019 to October 2020; randomised 1:1
- Enrolled April 2019 to October 2020; randomised 1:1
Primary result
As reported in the abstract
P = 0.751
Secondary outcomes
Total complications
P = 0.743
Predictor of infectious complications: old age
| OR (95% CI) | P value | ||
|---|---|---|---|
| Old ageOnly significant predictive factor | 2.990 (1.179–7.586) | P = 0.021 | |
| 0.10.31310Odds ratio (log scale) |
Hospital LOS
P = 0.635
| Outcome | Immunonutrition | Normal diet | P value |
|---|---|---|---|
| Overall change in body weight | P = 0.379 | ||
| Weight change after discharge | +0.4 ± 2.1 kg | −0.7 ± 2.3 kg | P = 0.002 |
Overall change in body weight
- Similar between the two groups
Weight change after discharge
- Only the immunonutrition group showed weight recovery after discharge
Original publication
Impact of Preoperative Immunonutrition on the Outcomes of Colon Cancer Surgery: Results from a Randomized Controlled Trial. Ann Surg. Published 4 August 2021. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →