Cardiothoracic & vascular anesthesia

Impact of Pressure Recovery Adjustment on Aortic Valve Area Classification of Disease Severity in Transcatheter Aortic Valve Replacement Patients

J Cardiothorac Vasc AnesthPublished Retrospective observational study

Authors' conclusion

Adjusting calculated AVA for PR resulted in a reclassification of a significant number of adult patients from severe to moderate aortic stenosis.

Study context

Population
Adults (≥18 years old) with severe aortic stenosis who underwent transcatheter aortic valve implantation (TAVI) at a quaternary-care academic centre, October 2013–February 2021
Participants
342 adults
Exposure
Pressure recovery (PR)-adjusted vs unadjusted aortic valve area (AVA) for aortic stenosis severity grading
  • Reclassifiedn = 81reference
Outcome
Reclassification from severe to moderate aortic stenosis (AVA >1.0 cm²) with PR-adjusted AVA
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Patients reclassified from severe to moderate aortic stenosis

81

24%

Observational data: associations, not effects.

Further findings

OutcomeReclassifiedP value
Left ventricle mass indexRemained severe vs Reclassified90.15 ± 24.03P = < 0.000001
Sinotubular junction (STJ) diameter >3.0 cm among reclassified
28% · 23 of 81
  • Left ventricle mass index: Remained severe 100.47 ± 28.77

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Impact of Pressure Recovery Adjustment on Aortic Valve Area Classification of Disease Severity in Transcatheter Aortic Valve Replacement Patients. J Cardiothorac Vasc Anesth. Published 29 February 2024. doi:10.1053/j.jvca.2024.02.036

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