Cardiothoracic & vascular anesthesia
Impact of prolonged cardiopulmonary bypass on gastrointestinal complications in cardiac surgery: a retrospective cohort study
Authors' conclusion
Prolonged CPB (≥ 120 min), hypertension, LVEF, and aortic surgery are significant risk factors for GICs following cardiac surgery with CPB.
Study context
- Population
- Patients undergoing cardiac surgery with cardiopulmonary bypass (CPB), January 2018–December 2023single centre
- Participants
- 1,444 patients
- Exposure
- Prolonged CPB vs normal CPB
- Prolonged CPBn = 686
- Outcome
- Occurrence of gastrointestinal complications (GICs)
- Follow-up
- Within 30 days post-surgery
Methodological detailssingle-center, propensity score matched (1:2)
- Single-center
- Propensity score matched (1:2)
Main finding
As reported in the abstract
GICs incidence after Propensity Score Matching (PSM) · 30 days
P = 0.041
Observational data: associations, not effects.
Further findings
Independent risk factors for gastrointestinal complications (GICs) (multivariate logistic regression)
| OR (95% CI) | P value | ||
|---|---|---|---|
| Prolonged CPB (≥ 120 min) | 1.86 (1.06–3.26) | P = 0.029 | |
| Hypertension | 1.86 (1.01–3.44) | P = 0.049 | |
| LVEF | 0.92 (0.88–0.96) | P < 0.001 | |
| Aortic surgery | 2.72 (1.20–6.19) | P = 0.017 | |
| 0.10.31310Odds ratio (log scale) |
Overall GICs incidence (all patients)
- Overall GICs incidence
- 8.59% (124/1444)
Ventilator time and in-hospital costs
- Prolonged ventilator time and higher in-hospital costs more prevalent in the prolonged CPB group
Original publication
Impact of prolonged cardiopulmonary bypass on gastrointestinal complications in cardiac surgery: a retrospective cohort study. Perioper Med (Lond). Published 15 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →