Respiratory failure & ventilation
Impact of Prone Position in COVID-19 Patients on Extracorporeal Membrane Oxygenation*
Main finding · In-hospital mortalityResult — go to the resultOdds ratio 0.49 CI 0.29–0.84Authors' conclusion
Prone position may be beneficial in patients supported by venovenous ECMO for COVID-19-related ARDS but more data are needed to draw definitive conclusions.
Study context
- Population
- Patients on venovenous extracorporeal membrane oxygenation (ECMO) for COVID-19-related acute respiratory distress syndrome (ARDS), 41 centresof 647 in 41 centres
- Participants
- 517 patients
- Exposure
- Prone vs supine position during venovenous ECMO
- Pronen = 364
- Supinen = 153reference
- Outcome
- In-hospital mortality
Methodological detailsmulticentre, propensity-score matched
- Multicentre
- Propensity-score matched
Main finding
As reported in the abstract
Odds ratio
0.49
CI 0.29–0.84
P = 0.010
Events by group
Prone vs Supine
OR 0.49 (CI 0.29–0.84); P = 0.010
Observational data: associations, not effects.
Further findings
Mortality, propensity score-matched pairs
P = 0.085
Mortality, patients alive at decannulation (propensity-matched)
P = 0.029
- Mortality, propensity score-matched pairs: 153 propensity score-matched pairs
Original publication
Impact of Prone Position in COVID-19 Patients on Extracorporeal Membrane Oxygenation*. Crit Care Med. Published 11 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →