Impact of psychosocial factors on the success of neuromodulation treatment for patients with persistent pain
Authors' conclusion
We found that patients with high levels of depression, anxiety, and sleep disturbance using the PROMIS CAT were predictive of unsuccessful trials. In addition, we found that patients with successful SCS trials reported lower levels of these domains on PROMIS CAT administered at the end of the trial.
Study context
- Population
- Patients with persistent pain undergoing an spinal cord stimulation (SCS) trial58 with successful electrode placement
- Participants
- 60 patients
- Exposure
- Successful vs unsuccessful SCS trial
- Unsuccessful trialn = 11reference
- Outcome
- Association of PROMIS CAT measures (pain interference, depression, anxiety, physical functioning, sleep disturbance) with successful SCS trial
Main finding
As reported in the abstract
Pre-trial PROMIS CAT scores · pre-trial
- Successful trial: lower pre-trial anxiety, depression and sleep disturbance
- No differences in demographics between successful and unsuccessful trial
Observational data: associations, not effects.
Further findings
Post-trial PROMIS CAT scores
- Successful trial: decreased post-trial depression, sleep disturbance and pain interference
Original publication
Impact of psychosocial factors on the success of neuromodulation treatment for patients with persistent pain. Reg Anesth Pain Med. Published 21 February 2024. doi:10.
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