Perioperative medicine & outcomes

Impact of spinal or epidural anaesthesia on perioperative outcomes in adult noncardiac surgery: a narrative review of recent evidence

Br J AnaesthPublished Narrative review

Authors' conclusion

Evidence of positive impact of neuraxial techniques is best established for the domains of patient comfort, pulmonary complications, and mortality, particularly in the setting of major open thoracoabdominal surgery.

Study context

Population
Adults undergoing noncardiac surgery
Comparison
Spinal or epidural anaesthesia/analgesia and perioperative outcomes
Methodological detailsLiterature searched 2018-2023: primary and secondary research, opinion pieces and guidelines
  • Literature searched 2018-2023: primary and secondary research, opinion pieces and guidelines

Main finding

As reported in the abstract

  • Convincing evidence of benefit of epidural analgesia on patient comfort after major open thoracoabdominal surgery
  • Recent evidence of benefit in prevention of pulmonary complications and mortality
  • Less certain experimental evidence for an impact on other outcome domains (cancer, renal, infection, cardiovascular), despite mechanistic plausibility and supportive observational evidence

Original publication

Impact of spinal or epidural anaesthesia on perioperative outcomes in adult noncardiac surgery: a narrative review of recent evidence. Br J Anaesth. Published 28 May 2024. doi:10.1016/j.bja.2024.04.044

Composed by AI from the published abstract and checked against it. How Briefs are made →

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