Perioperative medicine & outcomes
Impact of spinal or epidural anaesthesia on perioperative outcomes in adult noncardiac surgery: a narrative review of recent evidence
Authors' conclusion
Evidence of positive impact of neuraxial techniques is best established for the domains of patient comfort, pulmonary complications, and mortality, particularly in the setting of major open thoracoabdominal surgery.
Study context
- Population
- Adults undergoing noncardiac surgery
- Comparison
- Spinal or epidural anaesthesia/analgesia and perioperative outcomes
Methodological detailsLiterature searched 2018-2023: primary and secondary research, opinion pieces and guidelines
- Literature searched 2018-2023: primary and secondary research, opinion pieces and guidelines
Main finding
As reported in the abstract
- Convincing evidence of benefit of epidural analgesia on patient comfort after major open thoracoabdominal surgery
- Recent evidence of benefit in prevention of pulmonary complications and mortality
- Less certain experimental evidence for an impact on other outcome domains (cancer, renal, infection, cardiovascular), despite mechanistic plausibility and supportive observational evidence
Original publication
Impact of spinal or epidural anaesthesia on perioperative outcomes in adult noncardiac surgery: a narrative review of recent evidence. Br J Anaesth. Published 28 May 2024. doi:10. 1016/ j. bja. 2024. 04. 044
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