Pediatric anesthesia & critical care
Impact of Tumor Arterial Embolization on Hemodynamics During Surgical Resection of Pheochromocytoma and Paraganglioma in Children
Authors' conclusion
Although preoperative tumor arterial embolization did not significantly reduce overall intraoperative blood loss or hemodynamic instability in the entire cohort, it appears to effectively mitigate risk in children with larger, more biochemically active tumors, resulting in outcomes comparable to lower-risk cases managed without embolization.
Study context
- Population
- Children (aged 3–18 years) undergoing resection of pheochromocytoma or paraganglioma, Beijing Children's Hospital, January 2019 to June 2025
- Participants
- 31 children
- Exposure
- Preoperative tumor arterial embolization vs no embolization
- Embolizationn = 12
- Controln = 19reference
- Outcome
- Intraoperative SBP fluctuation amplitude
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- SBP fluctuation amplitude similar between groups
- Embolization vs Control: P = 0.393
Observational data: associations, not effects.
Further findings
Postoperative tumor necrosis
P = 0.002
Blood loss, time and AUC for SBP > 160 mmHg, ICU stay
- No differences observed
Safety
- Embolization-related stress cardiomyopathy
- 1 · events
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Impact of Tumor Arterial Embolization on Hemodynamics During Surgical Resection of Pheochromocytoma and Paraganglioma in Children. Acta Anaesthesiol Scand. Published 15 December 2025. doi:10.
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