Impact of renal complications on outcome in adult patients with acute fulminant myocarditis receiving venoarterial extracorporeal membrane oxygenation: an analysis of nationwide Chinese Society of ExtraCorporeal Life Support (CSECLS) database in China
Main finding · 30-day mortalityResult — go to the resultAdjusted odds ratio 3.120 95% CI 1.002–6.577Authors' conclusion
The onset of renal complications was significantly associated with 30-day mortality.
Study context
- Population
- Adults with acute fulminant myocarditis (AFM) receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO), Chinese Society of ExtraCorporeal Life Support (CSECLS) Registry
- Participants
- 202 adults
- Exposure
- Renal complications vs no renal complications during VA-ECMO
- Renal complicationsn = 94
- No renal complicationsn = 108reference
- Outcome
- 30-day mortality
- Follow-up
- 30 days
Methodological detailsnationwide registry, multivariable logistic regression
- Nationwide registry
- Multivariable logistic regression
Main finding
As reported in the abstract
Adjusted odds ratio
3.120
95% CI 1.002–6.577
P = 0.049
Events by group
Renal complications vs No renal complications
aOR 3.120 (95% CI 1.002–6.577); P = 0.049
Observational data: associations, not effects.
Further findings
Independent risk factors of renal complications
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Increasing age | 1.025 (1.008–1.298) | P = 0.040 | |
| Higher SOFA score | 1.162 (1.012–1.334) | P = 0.034 | |
| 0.512Adjusted odds ratio (log scale) |
Overall outcomes
- Weaned from ECMO
- 178 (88.1%)
- Survived
- 156 (71.9%)
- Developed renal complications on ECMO
- 94(46.5%)
- Median ECMO duration, h (IQR 112.1-188.8 h)
- 142.9
Original publication
Impact of renal complications on outcome in adult patients with acute fulminant myocarditis receiving venoarterial extracorporeal membrane oxygenation: an analysis of nationwide CSECLS database in China. Ann Intensive Care. Published 27 September 2023. doi:10.
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