Cardiothoracic & vascular anesthesia
Implementation of a goal directed perfusion strategy to reduce cardiac surgery associated kidney injury: A before and after study
Main findingResult — go to the resultOdds ratio 0.37 95 % CI 0.27–0.52Authors' conclusion
GDP strategy implantation during CPB is associated with a reduction of postoperative AKI.
Study context
- Population
- All patients admitted to a surgical intensive care unit (ICU) after cardiac surgery with cardiopulmonary bypass (CPB)
- Participants
- 903 patients
- Exposure
- Goal directed perfusion during CPB vs no Goal Directed Perfusion (GDP)
- Outcome
- Incidence of AKI according to KDIGO classification
Main finding
As reported in the abstract
Odds ratio
0.37
95 % CI 0.27–0.52
P < 0.001
Events by group
GDP vs No-GDP
OR 0.37 (95 % CI 0.27–0.52); P < 0.001
Observational data: associations, not effects.
Secondary outcomes
Acute kidney injury (AKI) by stage
- Benefit significant for stage 1 AKI, not stage 2 or 3 AKI
ICU mortality, LOS and other post-operative complications
- GDP not associated with a change in post-operative ICU mortality, LOS or any other post-operative complication
Original publication
Implementation of a goal directed perfusion strategy to reduce cardiac surgery associated kidney injury: A before and after study. J Clin Anesth. Published 16 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →