Respiratory failure & ventilation
Incidence and Outcome of Pneumomediastinum in Non-ICU Hospitalized COVID-19 Patients*
Authors' conclusion
Non-ICU hospitalized patients with COVID-19 have a high incidence of PNM, increasing the risk for intubation and mortality three- to four-fold, particularly in those with extensive lung damage.
Study context
- Population
- Non-ICU hospitalized patients with severe-to-critical COVID-19 pneumonia
- Participants
- 331 participants
- Exposure
- Pneumomediastinum (PNM) vs no PNM
- PNMn = 48
- Outcome
- Incidence of PNM
Methodological detailssingle-setting, tertiary-care level COVID treatment center
- Single-setting
- Tertiary-care level COVID treatment center
Main finding
As reported in the abstract
PNM
14.5%
48
Observational data: associations, not effects.
Further findings
Risk factors for PNM
| OR | P value | |
|---|---|---|
| CT-Scan Severity score >15Observed in 35.2% of participants (95% CI, 26.2-44.9%) | 4.09 | P = 0.002 |
| NIV | 4.46 | P = 0.005 |
| Outcome | HR | P value |
|---|---|---|
| Intubation | 3.72 | P < 0.001 |
| Mortality | 3.27 | P < 0.001 |
- Intubation — Intubated, all patients
- 50 (15%)
- Mortality — Died, all patients
- 88 (27%)
Risk factors for PNM
- No positive association with airway pressures
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Incidence and Outcome of Pneumomediastinum in Non-ICU Hospitalized COVID-19 Patients*. Crit Care Med. Published 5 October 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →