Incidence and Predictors of Dysglycemia in Intensive Care Unit Patients: A Cohort Study
Authors' conclusion
In this study of acutely admitted adult ICU patients, hypoglycemia was most common on the first day whereas hyperglycemia displayed smaller daily variations. Septic shock, CKD, AKI, diabetes, surgical admission, and a higher SOFA score were associated with an increased risk of hypoglycemia. Diabetes, high admission glucose, and glucocorticoid administration were associated with an increased risk of hyperglycemia.
Study context
- Population
- Acutely admitted adult patients, mixed medical and surgical intensive care unit (ICU), Copenhagen University Hospital-North Zealand
- Participants
- 577 participants
- Outcome
- Incidence of dysglycemia (hyperglycemia, hypoglycemia, high glycemic variability)
- Follow-up
- First 5 days of admission
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Glucose (mmol/L), mean (SD ±2.2)
9.1
Time in 3.9-10 mmol/L, median (47-93)
75%
≥1 episode of hypoglycemia ≤ 3.9 mmol/L, 47 of 577
8.2%
Observational data: associations, not effects.
Further findings
Predictors identified on day one
- Nutritional therapy associated with increased time in target range
- High admission glucose, glucocorticoid treatment and DM associated with increased risk of hyperglycemia
- CKD, AKI, DM, septic shock, increased SOFA score and surgical admission associated with increased risk of hypoglycemia
Original publication
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