Perioperative medicine & outcomes
Incidence and relative risk of delirium after major surgery for patients with pre‐operative depression: a systematic review and meta‐analysis
Pooled result · Postoperative deliriumResult — go to the resultRelative risk 1.91 95% CI 1.68–2.17Authors' conclusion
Patients with a previous diagnosis of depression or clinically important depressive symptoms before surgery have substantially greater risk of experiencing delirium after surgery.
Study context
- Population
- Adults undergoing major surgery
- Participants
- 4,664,051 adults · 42 studies
- Comparison
- Pre-operative depression vs no pre-operative depression
- Outcome
- Postoperative delirium (incidence and relative risk)
- Follow-up
- Immediate postoperative period
Methodological detailsmultilevel random effects meta-analyses, subgroup analyses
- Multilevel random effects meta-analyses
- Subgroup analyses
Pooled result
Postoperative delirium
Relative risk
1.91
95% CI 1.68–2.17
By group
Pre-operative depression vs Without pre-operative depression
RR 1.91 (95% CI 1.68–2.17)
As reported in the abstract
Further pooled results
Postoperative delirium, cohorts overall
- Pooled incidence
- 21% (95% CI 11-33%, I2 = 99.8%)
Original publication
Incidence and relative risk of delirium after major surgery for patients with pre‐operative depression: a systematic review and meta‐analysis. Anaesthesia. Published 4 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →