Perioperative medicine & outcomes
Incidence and risk factors for lack of recovery in patients undergoing major abdominal noncardiac surgery in Sweden: a prospective observational study
Authors' conclusion
Half of the study group reported a lack of recovery at 1 week, with persistence at 1 month. Complications were common and strongly associated with lack of recovery. Although recovery is slower in patients with complications, most regain or exceed baseline levels by 1 year. Early lack of recovery was linked to reduced days alive and out of hospital.
Study context
- Population
- Adults undergoing major noncardiac surgery at two Swedish hospitals, nested in the Myocardial Injury in Non-Cardiac Surgery in Sweden studyfollowed up to 1 yr
- Participants
- 124 adults
- Outcome
- Lack of recovery (≥6-point decrease in QoR-15 score from preoperative baseline): incidence and risk factors
Methodological detailspre-planned nested cohort, two-centre
- Pre-planned nested cohort
- Two-centre
Main finding
As reported in the abstract
Incidence of lack of recovery
Lack of recovery at 7-10 days
58%
Lack of recovery at 30 days
46%
Lack of recovery at 1 yr
24%
Observational data: associations, not effects.
Further findings
| Outcome | aOR (CI) | P value | |
|---|---|---|---|
| Complications as risk factor for lack of recovery · 30 daysComplications vs No complications · adjusted for age, ASA physical classification score, and sex | 2.60 (1.18–5.73) | P = 0.018 | |
| 0.20.5125Adjusted odds ratio (log scale) |
| Outcome | Mean difference (days) (CI) | P value | |
|---|---|---|---|
| DAOH at 30 days, early lack of recovery vs not3.7 fewer DAOH | −3.69 (−6.54 to −0.83) | P = 0.012 | |
| −10−505Difference, days (linear scale) |
- Complications as risk factor for lack of recovery — Complications occurred
- 49%
Complications as risk factor for lack of recovery · 30 days
- Lower QoR-15 scores and slower recovery over time with complications
Original publication
Incidence and risk factors for lack of recovery in patients undergoing major abdominal noncardiac surgery in Sweden: a prospective observational study. BJA Open. Published 29 July 2026. doi:10.
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