Cardiothoracic & vascular anesthesia
Perioperative myocardial injury is associated with increased postoperative non-cardiac complications in patients undergoing vascular surgery: a post hoc analysis of a randomised clinical pilot trial
Primary result · Non-cardiac complicationsResult — go to the resultAdjusted odds ratio 2.71 95% CI 1.33–5.55Authors' conclusion
In this pilot study, we found that new peri-operative myocardial injury is associated with an increased risk of non-cardiac complications within 30 days after index surgery in patients undergoing vascular surgery.
Study context
- Population
- Patients undergoing peripheral or aortic vascular surgery, 3 centres in Sweden, 2016–2019
- Participants
- 184 patients
- Comparison
- Perioperative myocardial injury vs no myocardial injury
- Primary endpoint
- Composite of major postoperative non-cardiac complications
- Follow-up
- 30 days
Methodological detailspilot
- Pilot
Primary result
Non-cardiac complications
Adjusted odds ratio
2.71
95% CI 1.33–5.55
P = 0.01
Myocardial injury vs No myocardial injury
aOR 2.71 (95% CI 1.33–5.55); P = 0.01
As reported in the abstract
- Primary endpoint occurred, all patients
- 67 (36%)
- Sensitivity of myocardial injury
- 0.40
- Specificity of myocardial injury
- 0.81
Further findings
Pre-operative hs-cTnT or NT-proBNP and non-cardiac complications
- No association found
Original publication
Perioperative myocardial injury is associated with increased postoperative non-cardiac complications in patients undergoing vascular surgery: a post hoc analysis of a randomised clinical pilot trial. Perioper Med (Lond). Published 13 November 2023. doi:10.
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