Perioperative medicine & outcomes
Incidence, diagnosis, management and outcome of acute mesenteric ischaemia: a prospective, multicentre observational study (AMESI Study)
Authors' conclusion
Nearly half of the patients with AMI died during their index hospitalization.
Study context
- Participants
- 705 participants
- Outcome
- Incidence, patient characteristics, diagnostic pathway, management and outcome of AMI
Methodological detailsmulticentre, 32 hospitals, High variability between participating sites for most variables
- Multicentre
- 32 hospitals
- High variability between participating sites for most variables
Main finding
As reported in the abstract
Acute mesenteric ischaemia (AMI) incidence, % of adult admissions
0.038%
Overall in-hospital mortality of AMI
49%
Overall 90-day mortality of AMI
53.3%
Observational data: associations, not effects.
Further findings
Reason for admission
- AMI primary reason for admission
- 69%
- AMI after admission with another diagnosis
- 31%
Time delays
h
- Median time symptom onset to admission (admitted due to AMI), IQR 9-48h
- 24
- Median time admission to diagnosis, IQR 1-12 h
- 6
AMI subtype
- Occlusive arterial, n (%)
- 231 (55.3%)
- Venous, n (%)
- 73 (17.5%)
- Non-occlusive (NOMI), n (%)
- 55 (13.2%)
- Other type, n (%)
- 11 (2.6%)
- Unclassified, n (%)
- 48 (11.5%)
Initial management
- Surgery, n (%)
- 242 (58%)
- Of surgery, revascularization, n (%)
- 59 (24.4%)
- Endovascular revascularization alone, n (%)
- 54 (13%)
- Conservative treatment, n (%)
- 76 (18%)
- Palliative care, n (%)
- 46 (11%)
- Revascularization in occlusive arterial AMI, n (%)
- 104 (45%)
- Of these, at one site admitting selected patients, n (%)
- 40 (38%)
Mortality by subtype (in-hospital and 90-day)
- Venous AMI (lowest), in-hospital / 90-day
- 13.7% and 16.4%
- NOMI (highest), in-hospital / 90-day
- 72.7% and 74.5%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Incidence, diagnosis, management and outcome of acute mesenteric ischaemia: a prospective, multicentre observational study (AMESI Study). Crit Care. Published 23 January 2024. doi:10.
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