Perioperative medicine & outcomes
Remote ischaemic preconditioning and survival in noncardiac surgery: a meta-analysis of randomised trials
Pooled result · Mortality (28 RCTs)Result — go to the resultRelative risk 0.74 95% CI 0.57–0.98Authors' conclusion
Remote ischaemic preconditioning was associated with improved survival and reduced postoperative stroke and hospital stay in noncardiac surgery.
Study context
- Population
- Adults undergoing noncardiac surgery
- Participants
- 7,457 adults · 72 randomised controlled trials (RCTs)
- Comparison
- Remote ischaemic preconditioning (RIPC) vs control
- Outcome
- Mortality
- Follow-up
- Longest available
Methodological detailsrandom-effects, Bayesian analysis
- Random-effects
- Bayesian analysis
Pooled result
Mortality (28 RCTs)
Relative risk
0.74
95% CI 0.57–0.98
P = 0.03
Events by group
RIPC vs Control
RR 0.74 (95% CI 0.57–0.98); P = 0.03
As reported in the abstract
- NNT
- 67
- Probability of any reduction in mortality
- 97.0%
Further pooled results
Postoperative stroke
- Reduced incidence with RIPC
- Moderate certainty
Hospital LOS
- Shorter with RIPC
- Low certainty
Original publication
Remote ischaemic preconditioning and survival in noncardiac surgery: a meta-analysis of randomised trials. Br J Anaesth. Published 3 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →