Incidence and Outcomes of Patients Receiving Chronic Kidney Replacement Therapy Admitted to Scottish ICUs Between 2009 and 2019—A National Observational Cohort Study
Authors' conclusion
With a growing population of kidney transplant recipients and the improved survival of patients on chronic dialysis, the number of ICU admissions is rising in the chronic KRT population. Mortality post-ICU admission is high for these patients.
Study context
- Population
- Adults receiving chronic kidney replacement therapy (KRT) (maintenance dialysis or kidney transplant) in Scotland admitted to ICU, 2009–2019of 10,657 registered
- Participants
- 1,402 adults
- Exposure
- Chronic dialysis vs kidney transplant recipients
- Outcome
- ICU admission rate
Methodological detailsnational, observational
- National
- Observational
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
Factors associated with death at 30 days post-ICU admission
| HR (95% CI) | ||
|---|---|---|
| Invasive ventilationAdjusted Cox PH model | 1.75 (1.28–2.39) | |
| Vasoactive drugsAdjusted Cox PH model | 1.72 (1.28–2.31) | |
| 0.512Hazard ratio (log scale) |
| Outcome | Chronic dialysis | Kidney transplant |
|---|---|---|
| Reason for ICU admission | ||
| Renal reasons (most common) | 20.9% | — not stated in the abstract |
| Pneumonia | — not stated in the abstract | 19.3% |
| Sepsis | — not stated in the abstract | 12.8% |
— not stated in the abstract
Post-ICU mortality · 30 d and 1 year
- Similar in dialysis and transplant patients: about 24% at 30 d
- Similar in dialysis and transplant patients: about 40% at 1 year
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Incidence and Outcomes of Patients Receiving Chronic Kidney Replacement Therapy Admitted to Scottish ICUs Between 2009 and 2019—A National Observational Cohort Study. Crit Care Med. Published 15 November 2022. doi:10. 1097/ ccm. 0000000000005710
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