Organ support & nutrition

Incidence and Outcomes of Patients Receiving Chronic Kidney Replacement Therapy Admitted to Scottish ICUs Between 2009 and 2019—A National Observational Cohort Study

Crit Care MedPublished Retrospective cohort study

Authors' conclusion

With a growing population of kidney transplant recipients and the improved survival of patients on chronic dialysis, the number of ICU admissions is rising in the chronic KRT population. Mortality post-ICU admission is high for these patients.

Study context

Population
Adults receiving chronic kidney replacement therapy (KRT) (maintenance dialysis or kidney transplant) in Scotland admitted to ICU, 2009–2019of 10,657 registered
Participants
1,402 adults
Exposure
Chronic dialysis vs kidney transplant recipients
Outcome
ICU admission rate
Methodological detailsnational, observational
  • National
  • Observational

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

Factors associated with death at 30 days post-ICU admission

HR (95% CI)
Invasive ventilationAdjusted Cox PH model1.75 (1.28–2.39)
Vasoactive drugsAdjusted Cox PH model1.72 (1.28–2.31)
OutcomeChronic dialysisKidney transplant
Reason for ICU admission
Renal reasons (most common)20.9%— not stated in the abstract
Pneumonia— not stated in the abstract19.3%
Sepsis— not stated in the abstract12.8%

— not stated in the abstract

Post-ICU mortality · 30 d and 1 year

Similar in dialysis and transplant patients: about 24% at 30 d
Similar in dialysis and transplant patients: about 40% at 1 year

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Incidence and Outcomes of Patients Receiving Chronic Kidney Replacement Therapy Admitted to Scottish ICUs Between 2009 and 2019—A National Observational Cohort Study. Crit Care Med. Published 15 November 2022. doi:10.1097/ccm.0000000000005710

Composed by AI from the published abstract and checked against it. How Briefs are made →

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