Paediatric anaesthesia & critical care

Incidence, Predictors, and Outcomes of Early Postoperative Dysnatremia After Pediatric Neurosurgery: A Prospective Observational Study

Paediatr AnaesthPublished Prospective observational study

Authors' conclusion

About one-in-five children undergoing neurosurgery develop postoperative dysnatremia, and it is predicted by preoperative dysnatremia, sellar/suprasellar pathology, and higher blood loss. Dysnatremia is associated with poor clinical outcomes.

Study context

Population
Children aged < 18 years undergoing elective neurosurgery22-month study period
Participants
668 children
Outcome
Incidence of postoperative dysnatremia (serum sodium < 135 or > 145 mEq/L)
Follow-up
First 3 postoperative days
Methodological detailssingle-center, consecutive patients
  • Single-center
  • Consecutive patients

Main finding

As reported in the abstract

Incidence of postoperative dysnatremia

Incidence of postoperative dysnatremia

18.6%

124/668

Observational data: associations, not effects.

Further findings

Predictors of postoperative dysnatremia (multivariate regression)

Sellar/suprasellar pathologies, preoperative dysnatremia and higher blood loss were predictors

Outcomes with postoperative dysnatremia

Higher occurrence of seizures, neurological deterioration and death, and longer intensive care unit (ICU) and hospital stays

Original publication

Incidence, Predictors, and Outcomes of Early Postoperative Dysnatremia After Pediatric Neurosurgery: A Prospective Observational Study. Paediatr Anaesth. Published 29 July 2026. doi:10.1002/pan.70274

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